Droplet generation system

作者：Ian Roger Munro | Daniel Keppie McCluskey | Loic Marie Coudron

发明人：Ian Roger Munro | Daniel Keppie McCluskey | Loic Marie Coudron

所有人：University of Hertfordshire Higher Education Corporation 年：2022,

语种：英语

公开国家：GB 国家：英国

专利申请号：GB2012504-3 专利申请日期：2020-08-11

公开(公告)号：GB-2597958-A 公开日期：2022-02-16

分类号：B01L-3/00 国际主分类号：B01L-3/00 国际分类号：B01L-3/00

摘要：Abstract Title: Apparatus for introducing and/or removing fluid droplets to a fluidic systemAn apparatus 10 for introducing and/or removing a fluid droplet to/from a fluidic system, the apparatus comprising a first substrate 12 and a working surface 14 wherein the first substrate is provided with an aperture 16a, 16b and the droplet is introduced onto/removed from the working surface through the aperture. Ideally, the system is a microfluidic system such as an electrowetting on dielectric system (EWOD) with the aperture being a through hole via (THV) formed in an electrode of the electrode array 14 and the first substrate is a printed circuit board (PCB). Alternatively, the system is a Laplace pressure gradient self-propulsion system (fig 6). Preferably, aperture diameter is smaller than droplet diameter and is configured to allow the droplet to move across the aperture. The working surface may be part of the first substrate or be part of a second substrate. The system may comprise a plurality of apertures for introducing and/or removing droplets. The apparatus further comprises a fluid supply reservoir 20, a removed fluid reservoir 34, means for moving the fluid through the aperture 22, 30 in the form of pressure driven means such as diaphragm pumps or vacuum driven means in the form of reverse syringes, and means to determine the presence of a droplet.