SYSTEMS AND METHODS FOR PERFUSING A HUMAN PLACENTA

作者：Grant, Patricia Ellen | Roberts, Drucilla | Turk, Esra Abaci | Stout, Jeffrey N. | Wald, Lawrence L. | Adalsteinsson, Elfar | Barth, William

发明人：Grant, Patricia Ellen | Roberts, Drucilla | Turk, Esra Abaci | Stout, Jeffrey N. | Wald, Lawrence L. | Adalsteinsson, Elfar | Barth, William

所有人：Children's Medical Center Corporation | Massachusetts Institute of Technology | The General Hospital Corporation 年：2022,

语种：英语

公开国家：US 国家：美国

专利申请号：US17-553999 专利申请日期：2021-12-17

公开(公告)号：US-20220192177-A1 公开日期：2022-06-23

分类号：A01N-1/02 国际主分类号：A01N-1/02 国际分类号：A01N-1/02 | A61B-5/055 | G01R-33/30 | G01R-33/58

摘要：Provided herein are systems and methods for development and use of a perfusion apparatus comprising a biological phantom created from an ex vivo placenta. In some embodiments, a system is provided for perfusing an ex vivo placenta to be imaged using a magnetic resonance imaging (MRI) device, the system comprising a chamber configured to house the ex vivo placenta therein, the chamber including a first partition separating the chamber into a first portion and a second portion, wherein the ex vivo placenta is housed at least partially in the first portion, and at least one first inlet disposed in the second portion for receiving at least one first tube, the at least one first tube being configured to couple at least one first pump to a fetal compartment of the ex vivo placenta when present in the chamber.